UGT1A1 polymorphisms in cancer: impact on irinotecan treatment

Masashi Takano1 Toru Sugiyama2 1Department of Clinical Oncology, National Defense Medical College Hospital, Tokorozawa, Saitama, 2Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Iwate, Japan Abstract: Mutations in the UGT1A1 gene have been implicated in Gilbert syndrome,...

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Bibliographic Details
Main Authors: Takano M, Sugiyama T
Format: Article
Language:English
Published: Dove Medical Press 2017-02-01
Series:Pharmacogenomics and Personalized Medicine
Subjects:
Online Access:https://www.dovepress.com/ugt1a1-polymorphisms-in-cancer-impact-on-irinotecan-treatment-peer-reviewed-article-PGPM