Identification of novel bacterial DNA gyrase inhibitors: An in silico study

Owing to essential role in bacterial survival, DNA gyrase has been exploited as a validated drug target. However, rapidly emerging resistance to gyrase-targeted drugs such as widely utilized fluoroquinolones reveals the necessity to develop novel compounds with new mechanism of actions against this...

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Bibliographic Details
Main Authors: Hamzeh Rahimi, Ali Najafi, Habib Eslami, Babak Negahdari, Mehrdad Moosazadeh Moghaddam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
Online Access:http://www.jrps.ir/article.asp?issn=1735-5362;year=2016;volume=11;issue=3;spage=250;epage=258;aulast=Rahimi