Identification of novel bacterial DNA gyrase inhibitors: An in silico study
Owing to essential role in bacterial survival, DNA gyrase has been exploited as a validated drug target. However, rapidly emerging resistance to gyrase-targeted drugs such as widely utilized fluoroquinolones reveals the necessity to develop novel compounds with new mechanism of actions against this...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2016-01-01
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Series: | Research in Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.jrps.ir/article.asp?issn=1735-5362;year=2016;volume=11;issue=3;spage=250;epage=258;aulast=Rahimi |