Administration of the Antioxidant N-Acetyl-Cysteine in Pregnant Mice Has Long-Term Positive Effects on Metabolic and Behavioral Endpoints of Male and Female Offspring Prenatally Exposed to a High-Fat Diet

Administration of the Antioxidant N-Acetyl-Cysteine in Pregnant Mice Has Long-Term Positive Effects on Metabolic and Behavioral Endpoints of Male and Female Offspring Prenatally Exposed to a High-Fat Diet

A growing body of evidence suggests the consumption of high-fat diet (HFD) during pregnancy to model maternal obesity and the associated increase in oxidative stress (OS), might act as powerful prenatal stressors, leading to adult stress-related metabolic or behavioral disorders. We hypothesized tha...

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Bibliographic Details
Main Authors: Alessandra Berry, Veronica Bellisario, Pamela Panetta, Carla Raggi, Maria C. Magnifico, Marzia Arese, Francesca Cirulli
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
N-acetyl-cysteine
high-fat diet
pregnancy
metabolism
oxidative stress
behavior
Online Access:http://journal.frontiersin.org/article/10.3389/fnbeh.2018.00048/full

Internet

http://journal.frontiersin.org/article/10.3389/fnbeh.2018.00048/full

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