Monoclonal antibody to rat apoC: multiple binding to apoC-I on lipoproteins increases its affinity constant.

Using solid phase systems, the kinetics of binding of monoclonal antibody (LRB 45, IgG2b,kappa) to apoC-I and apoC-I on lipoproteins were investigated. At 25 degrees C, the association constant of LRB 45 antibody to apoC-I (3.56 X 10(6) M-1 X sec-1) was almost three times slower than the association...

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Bibliographic Details
Main Author: L Wong
Format: Article
Language:English
Published: Elsevier 1985-07-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752034308X