Tumor Cells Modified with Newcastle Disease Virus Expressing IL-24 as a Cancer Vaccine

Tumor Cells Modified with Newcastle Disease Virus Expressing IL-24 as a Cancer Vaccine

Interleukin-24 (IL-24) is a promising agent for cancer immunotherapy that induces apoptosis of tumor cells and enhances T cell activation and function. In order to improve the antitumor activity induced by Newcastle disease virus (NDV)-modified tumor vaccine, we generated a recombinant NDV expressin...

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Bibliographic Details
Main Authors: Xiaojing Xu, Cheng Yi, Xiaoqin Yang, Jianwei Xu, Qing Sun, Yonghao Liu, Lixiang Zhao
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770519300634

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http://www.sciencedirect.com/science/article/pii/S2372770519300634

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