A Novel Microtubule-Tau Association Enhancer and Neuroprotective Drug Candidate: Ac-SKIP

Activity-dependent neuroprotective protein (ADNP) has been initially discovered through its eight amino acid sequence NAPVSIPQ, which shares SIP motif with SALLRSIPA – a peptide derived from activity-dependent neurotrophic factor (ADNF). Mechanistically, both NAPVSIPQ and SALLRSIPA contain a SIP mot...

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Bibliographic Details
Main Authors: Yanina Ivashko-Pachima, Illana Gozes
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
tau
EBs
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00435/full