Cell kinetic studies fail to identify sequentially proliferating progenitors as the major source of epithelial renewal in the adult murine prostate.

There is evidence that stem cells and their progeny play a role in the development of the prostate. Although stem cells are also considered to give rise to differentiated progeny in the adult prostate epithelium ex vivo, the cohort of adult prostate stem cells in vivo as well as the mechanisms by wh...

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Bibliographic Details
Main Authors: Jean-Christophe Pignon, Chiara Grisanzio, Ingrid Carvo, Lillian Werner, Meredith Regan, E Lynette Wilson, Sabina Signoretti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4449166?pdf=render