AIM for Allostery: Using the Ising Model to Understand Information Processing and Transmission in Allosteric Biomolecular Systems

AIM for Allostery: Using the Ising Model to Understand Information Processing and Transmission in Allosteric Biomolecular Systems

In performing their biological functions, molecular machines must process and transmit information with high fidelity. Information transmission requires dynamic coupling between the conformations of discrete structural components within the protein positioned far from one another on the molecular sc...

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Bibliographic Details
Main Authors: Michael V. LeVine, Harel Weinstein
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Entropy
Subjects:
allostery
biophysics
Ising model
statistical mechanics
signal transduction
information theory
G protein coupled receptors (GPCRs)
dopamine D2 receptor
functional selectivity
Online Access:http://www.mdpi.com/1099-4300/17/5/2895

Internet

http://www.mdpi.com/1099-4300/17/5/2895

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