Altered balance of activity in the striatal direct and indirect pathways in mouse models of Huntington’s disease
Imbalance in the activity of striatal direct and indirect pathway neurons contributes to motor disturbances in several neurodegenerative diseases. In Huntington’s disease (HD), indirect pathway [dopamine (DA) D2 receptor-expressing)] medium-sized spiny neurons (MSNs) are believed to show earlier vul...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2011-06-01
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| Series: | Frontiers in Systems Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsys.2011.00046/full |