Programmed death-1 and its ligand are novel immunotolerant molecules expressed on leukemic B cells in chronic lymphocytic leukemia.

Programmed death-1 and its ligand are novel immunotolerant molecules expressed on leukemic B cells in chronic lymphocytic leukemia.

Programmed death-1 (PD-1) is an immunoreceptor predominantly expressed on exhausted T cells, which through an interaction with its ligand (PD-L1), controls peripheral tolerance by limiting effector functions of T lymphocytes. qRT-PCR for PD-1, PD-L1 and their splicing forms as well as flow cytometri...

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Main Authors: Maciej Grzywnowicz, Joanna Zaleska, Daniel Mertens, Waldemar Tomczak, Paulina Wlasiuk, Kamila Kosior, Agnieszka Piechnik, Agnieszka Bojarska-Junak, Anna Dmoszynska, Krzysztof Giannopoulos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22532845/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22532845/?tool=EBI

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