Recombinant Adiponectin Induces the Production of Pro-Inflammatory Chemokines and Cytokines in Circulating Mononuclear Cells and Fibroblast-Like Synoviocytes From Non-Inflamed Subjects

Recombinant Adiponectin Induces the Production of Pro-Inflammatory Chemokines and Cytokines in Circulating Mononuclear Cells and Fibroblast-Like Synoviocytes From Non-Inflamed Subjects

Adiponectin is an adipokine with a modulatory role in metabolism and exerting both anti- and pro-inflammatory effects. Levels of adiponectin are increased in serum and synovial fluid from patients with rheumatoid arthritis (RA). Adiponectin is able to stimulate the production of different pro-inflam...

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Bibliographic Details
Main Authors: Yuan Zhang, Jonathan Aldridge, Georgios K. Vasileiadis, Helena Edebo, Anna-Karin H. Ekwall, Anna-Carin Lundell, Anna Rudin, Cristina Maglio
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
adiponectin
inflammation
chemokines
cytokines
peripheral blood mononuclear cells
fibroblast-like synoviocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.569883/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.569883/full

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