Trypanosoma brucei RAP1 Has Essential Functional Domains That Are Required for Different Protein Interactions
Trypanosoma brucei causes human African trypanosomiasis and regularly switches its major surface antigen, VSG, to evade the host immune response. VSGs are expressed from subtelomeres in a monoallelic fashion. TbRAP1, a telomere protein, is essential for cell viability and VSG monoallelic expression...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2020-02-01
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Series: | mSphere |
Subjects: | |
Online Access: | https://doi.org/10.1128/mSphere.00027-20 |