Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression

Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression

Chromatin structure plays a significant role in the regulation of gene expression. Here the authors show that TFIIH interacts with the histone acetyl transferase KAT2A and recruits the ATAC/hSAGA complexes to chromatin; and that loss of xeroderma pigmentosum group B (XPB) function results in chromat...

Full description

Bibliographic Details
Main Authors: Jérémy Sandoz, Zita Nagy, Philippe Catez, Gizem Caliskan, Sylvain Geny, Jean-Baptiste Renaud, Jean-Paul Concordet, Arnaud Poterszman, Laszlo Tora, Jean-Marc Egly, Nicolas Le May, Frédéric Coin
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09270-2

Internet

https://doi.org/10.1038/s41467-019-09270-2

Similar Items