Bradykinin [corrected] B1 receptor antagonism is beneficial in renal ischemia-reperfusion injury.

Previously we have demonstrated that bradykinin B1 receptor deficient mice (B1KO) were protected against renal ischemia and reperfusion injury (IRI). Here, we aimed to analyze the effect of B1 antagonism on renal IRI and to study whether B1R knockout or antagonism could modulate the renal expression...

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Main Authors: Pamella H M Wang, Gabriela Campanholle, Marcos A Cenedeze, Carla Q Feitoza, Giselle M Gonçalves, Richardt G Landgraf, Sonia Jancar, João B Pesquero, Alvaro Pacheco-Silva, Niels O S Câmara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2516176?pdf=render