TGF‐β‐induced IGFBP‐3 is a key paracrine factor from activated pericytes that promotes colorectal cancer cell migration and invasion

TGF‐β‐induced IGFBP‐3 is a key paracrine factor from activated pericytes that promotes colorectal cancer cell migration and invasion

The crosstalk between cancer cells and the tumor microenvironment has been implicated in cancer progression and metastasis. Fibroblasts and immune cells are widely known to be attracted to and modified by cancer cells. However, the role of pericytes in the tumor microenvironment beyond endothelium s...

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Bibliographic Details
Main Authors: Rocío Navarro, Antonio Tapia‐Galisteo, Laura Martín‐García, Carlos Tarín, Cesáreo Corbacho, Gonzalo Gómez‐López, Esther Sánchez‐Tirado, Susana Campuzano, Araceli González‐Cortés, Paloma Yáñez‐Sedeño, Marta Compte, Luis Álvarez‐Vallina, Laura Sanz
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Molecular Oncology
Subjects:
colorectal cancer
IGFBP‐3
pericyte
TGF‐β
tumor microenvironment
Online Access:https://doi.org/10.1002/1878-0261.12779

Internet

https://doi.org/10.1002/1878-0261.12779

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