Platelets in Amyloidogenic Mice Are Activated and Invade the Brain

Alzheimer’s disease (AD) is a neurodegenerative disease with a complex and not fully understood pathogenesis. Besides brain-intrinsic hallmarks such as abnormal deposition of harmful proteins, i.e., amyloid beta in plaques and hyperphosphorylated Tau in neurofibrillary tangles, blood-derived element...

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Bibliographic Details
Main Authors: Kathrin M. Kniewallner, Diana M. Bessa de Sousa, Michael S. Unger, Heike Mrowetz, Ludwig Aigner
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00129/full