A light-switching pyrene probe to detect phase-separated biomolecules

A light-switching pyrene probe to detect phase-separated biomolecules

Summary: Biomolecules may undergo liquid–liquid phase separation (LLPS) to spatiotemporally compartmentalize and regulate diverse biological processes. Because the number of tools to directly probe LLPS is limited (ie. FRAP, FRET, fluorescence microscopy, fluorescence anisotropy, circular dichroism,...

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Bibliographic Details
Main Authors: Masaharu Hazawa, Shogo Amemori, Yoshio Nishiyama, Yoshihiro Iga, Yuki Iwashima, Akiko Kobayashi, Hirohisa Nagatani, Motohiro Mizuno, Kenji Takahashi, Richard W. Wong
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:iScience
Subjects:
Biophysical Chemistry
Biological Sciences
Biochemistry
Biophysics
Biological Sciences Research Methodologies
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221008336

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http://www.sciencedirect.com/science/article/pii/S2589004221008336

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