Glycosylation of a Capsule-Like Complex (CLC) by Francisella novicida Is Required for Virulence and Partial Protective Immunity in Mice

Glycosylation of a Capsule-Like Complex (CLC) by Francisella novicida Is Required for Virulence and Partial Protective Immunity in Mice

Francisella tularensis is a Gram-negative bacterium and the etiologic agent of tularemia. F. tularensis may appear encapsulated when examined by transmission electron microscopy (TEM), which is due to production of an extracellular capsule-like complex (CLC) when the bacterium is grown under specifi...

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Bibliographic Details
Main Authors: Kelly C. Freudenberger Catanzaro, Anna E. Champion, Nrusingh Mohapatra, Thomas Cecere, Thomas J. Inzana
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Microbiology
Subjects:
Francisella novicida
capsule-like complex
virulence in mice
tularemia
glycosylation
protective immunity
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2017.00935/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2017.00935/full

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