Seminoma and embryonal carcinoma footprints identified by analysis of integrated genome-wide epigenetic and expression profiles of germ cell cancer cell lines.

Seminoma and embryonal carcinoma footprints identified by analysis of integrated genome-wide epigenetic and expression profiles of germ cell cancer cell lines.

BACKGROUND: Originating from Primordial Germ Cells/gonocytes and developing via a precursor lesion called Carcinoma In Situ (CIS), Germ Cell Cancers (GCC) are the most common cancer in young men, subdivided in seminoma (SE) and non-seminoma (NS). During physiological germ cell formation/maturation,...

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Bibliographic Details
Main Authors: Yvonne G van der Zwan, Martin A Rijlaarsdam, Fernando J Rossello, Amanda J Notini, Suzan de Boer, D Neil Watkins, Ad J M Gillis, Lambert C J Dorssers, Stefan J White, Leendert H J Looijenga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4041891?pdf=render

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http://europepmc.org/articles/PMC4041891?pdf=render

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