Reduced cellular susceptibility to in vitro HIV infection is associated with CD4+ T cell quiescence.

Reduced cellular susceptibility to in vitro HIV infection is associated with CD4+ T cell quiescence.

HIV preferentially establishes productive infection in activated CD4+ T cells. Since proportions of activated CD4+ T cells vary between individuals, this study aimed to determine if individuals with a greater proportion of activated CD4+ T cells would be more susceptible to in vitro HIV infection.Un...

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Bibliographic Details
Main Authors: Catherine M Card, W John Rutherford, Suzie Ramdahin, Xiaojian Yao, Makobu Kimani, Charles Wachihi, Joshua Kimani, Francis A Plummer, T Blake Ball, Keith R Fowke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3448692?pdf=render

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http://europepmc.org/articles/PMC3448692?pdf=render

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