IL-10 Producing B Cells Dampen Protective T Cell Response and Allow Chlamydia muridarum Infection of the Male Genital Tract

IL-10 Producing B Cells Dampen Protective T Cell Response and Allow Chlamydia muridarum Infection of the Male Genital Tract

A significant proportion of individuals develop chronic, persistent and recurrent genital tract infections with Chlamydia trachomatis, which has been attributed to the numerous strategies that the bacterium uses to subvert host immune responses. Animal chlamydia models have demonstrated that protect...

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Bibliographic Details
Main Authors: Leonardo R. Sanchez, Gloria J. Godoy, Melisa Gorosito Serrán, Maria L. Breser, Facundo Fiocca Vernengo, Pablo Engel, Ruben D. Motrich, Adriana Gruppi, Virginia E. Rivero
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
Chlamydia trachomatis
prostatitis
regulatory B cells
male genital tract
infection
IL-10
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00356/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00356/full

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