Protein Kinases and Transcription Factors Activation in Response to UV-Radiation of Skin: Implications for Carcinogenesis

Protein Kinases and Transcription Factors Activation in Response to UV-Radiation of Skin: Implications for Carcinogenesis

Solar ultraviolet (UV) radiation is an important environmental factor that leads to immune suppression, inflammation, photoaging, and skin carcinogenesis. Here, we reviewed the specific signal transduction pathways and transcription factors involved in the cellular response to UV-irradiation. Increa...

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Bibliographic Details
Main Authors: Laurence A. Marchat, Elena Aréchaga Ocampo, Mavil López Casamichana, Carlos Pérez-Plasencia, César López-Camarillo, Elizbeth Álvarez-Sánchez
Format: Article
Language:English
Published: MDPI AG 2011-12-01
Series:International Journal of Molecular Sciences
Subjects:
ultraviolet radiation
skin cancer
skin photoaging
p38
MAPK
JNK
ERK1/2
ATM
SKR kinases
NF-κB
AP-1
NRF2 transcription factors
Online Access:http://www.mdpi.com/1422-0067/13/1/142/

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http://www.mdpi.com/1422-0067/13/1/142/

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