Use of probiotics to reduce infections and death and prevent colonization with extended-spectrum beta-lactamase (ESBL)-producing bacteria among newborn infants in Tanzania (ProRIDE Trial): study protocol for a randomized controlled clinical trial

Use of probiotics to reduce infections and death and prevent colonization with extended-spectrum beta-lactamase (ESBL)-producing bacteria among newborn infants in Tanzania (ProRIDE Trial): study protocol for a randomized controlled clinical trial

Abstract Background Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) has emerged as an urgent global health threat and is by the World Health Organization ranked as priority 1 among pathogens in need of new treatment. Studies have shown high mortality in Tanzanian children with...

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Bibliographic Details
Main Authors: Kanika Kuwelker, Nina Langeland, Iren Høyland Löhr, Joshua Gidion, Joel Manyahi, Sabrina John Moyo, Bjørn Blomberg, Claus Klingenberg
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Trials
Subjects:
Newborn
Infants
Probiotics
Gut colonization
Extended-spectrum beta-lactamase
ESBL
Online Access:https://doi.org/10.1186/s13063-021-05251-3

Internet

https://doi.org/10.1186/s13063-021-05251-3

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