Efficacy of Cefquinome against Escherichia coli Environmental Mastitis Assessed by Pharmacokinetic and Pharmacodynamic Integration in Lactating Mouse Model

Efficacy of Cefquinome against Escherichia coli Environmental Mastitis Assessed by Pharmacokinetic and Pharmacodynamic Integration in Lactating Mouse Model

This work investigates the pharmacodynamic effectiveness of cefquinome against environmental Escherichia coli mastitis infection, following an intramammary administration. We established the pharmacokinetic and pharmacodynamic (PK/PD) model in lactating mice. The PK/PD parameters were identified to...

Full description

Bibliographic Details
Main Authors: Yang Yu, Jin-Tao Fang, Jian Sun, Mei Zheng, Qing Zhang, Jie-Shun He, Xiao-Ping Liao, Ya-Hong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Microbiology
Subjects:
cefquinome
Escherichia coli
environmental mastitis
dosage regimen
PK/PD
mouse model
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01445/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01445/full

Similar Items