E2F7 Transcriptionally Inhibits MicroRNA-199b Expression to Promote USP47, Thereby Enhancing Colon Cancer Tumor Stem Cell Activity and Promoting the Occurrence of Colon Cancer

E2F7 Transcriptionally Inhibits MicroRNA-199b Expression to Promote USP47, Thereby Enhancing Colon Cancer Tumor Stem Cell Activity and Promoting the Occurrence of Colon Cancer

microRNAs (miRNAs) can modulate the expression level of genes in a post-transcription manner, which are closely related to growth and metastasis of colon cancer. Herein, we aimed to explore how miR-199b influences colon cancer and to characterize its underlying molecular mechanism associating with E...

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Bibliographic Details
Main Authors: Xiong Guo, Ling Liu, Qi Zhang, Weiming Yang, Yang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
Subjects:
E2F7
USP47
MAPK
colon cancer 3
microRNA-199b
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.565449/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.565449/full

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