CARD15/NOD2 is required for Peyer's patches homeostasis in mice.

<h4>Background</h4>CARD15/NOD2 mutations are associated with susceptibility to Crohn's Disease (CD) and Graft Versus Host Disease (GVHD). CD and GVHD are suspected to be related with the dysfunction of Peyer's patches (PP) and isolated lymphoid follicles (LFs). Using a new mous...

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Main Authors: Frédérick Barreau, Ulrich Meinzer, Fabrice Chareyre, Dominique Berrebi, Michiko Niwa-Kawakita, Monique Dussaillant, Benoit Foligne, Vincent Ollendorff, Martine Heyman, Stéphane Bonacorsi, Thecla Lesuffleur, Ghislaine Sterkers, Marco Giovannini, Jean-Pierre Hugot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0000523