Local Administration of Caloric Restriction Mimetics to Promote the Immune Control of Lung Metastases

Caloric restriction mimetics (CRMs), compounds that mimic the biochemical effects of nutrient deprivation, administered via systemic route promote antitumor effects through the induction of autophagy and the modulation of the immune microenvironment; however, collateral effects due to metabolic chan...

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Bibliographic Details
Main Authors: Valentino Le Noci, Michele Sommariva, Francesca Bianchi, Tiziana Triulzi, Elda Tagliabue, Andrea Balsari, Lucia Sfondrini
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2019/2015892