The Duffy binding protein (PkDBPαII) of Plasmodium knowlesi from Peninsular Malaysia and Malaysian Borneo show different binding activity level to human erythrocytes

The Duffy binding protein (PkDBPαII) of Plasmodium knowlesi from Peninsular Malaysia and Malaysian Borneo show different binding activity level to human erythrocytes

Abstract Background The zoonotic Plasmodium knowlesi is a major cause of human malaria in Malaysia. This parasite uses the Duffy binding protein (PkDBPαII) to interact with the Duffy antigen receptor for chemokines (DARC) receptor on human and macaque erythrocytes to initiate invasion. Previous stud...

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Bibliographic Details
Main Authors: Khai Lone Lim, Amirah Amir, Yee Ling Lau, Mun Yik Fong
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Malaria Journal
Subjects:
Plasmodium knowlesi
Malaysia
Duffy binding protein
DARC
Erythrocyte binding
Online Access:http://link.springer.com/article/10.1186/s12936-017-1984-8

Internet

http://link.springer.com/article/10.1186/s12936-017-1984-8

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