Chimeric Antigen Receptor Therapy for B-cell Malignancies
<p>We presented data showing that the CART-19 cells expressing the 4-1BB signaling domain can have unprecedented and massive in-vivo expansion, traffic to tumor sites, persist long term in vivo, and induce rapid and potent anti-tumor activity in chemotherapy refractory CLL patients.</p>
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ivyspring International Publisher
2011-01-01
|
| Series: | Journal of Cancer |
| Online Access: | http://www.jcancer.org/v02p0331.htm |