The Genotoxin Colibactin Shapes Gut Microbiota in Mice

The Genotoxin Colibactin Shapes Gut Microbiota in Mice

Infections of genotoxic Escherichia coli spread concomitantly with urbanized progression. These bacteria may prompt cell senescence and affect DNA stability, inducing cancer via the production of colibactin, a genotoxin shown capable of affecting host DNA in eukaryotic cells. In this study, we show...

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Bibliographic Details
Main Authors: Sophie Tronnet, Pauline Floch, Laetitia Lucarelli, Deborah Gaillard, Patricia Martin, Matteo Serino, Eric Oswald
Format: Article
Language:English
Published: American Society for Microbiology 2020-07-01
Series:mSphere
Subjects:
colibactin
enterobacteria
gut microbiota dysbiosis
microbiome
Online Access:https://doi.org/10.1128/mSphere.00589-20

Internet

https://doi.org/10.1128/mSphere.00589-20

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