The role of Piezo1 in conventional aqueous humor outflow dynamics

Summary: Controlling intraocular pressure (IOP) remains the mainstay of glaucoma therapy. The trabecular meshwork (TM), the key tissue responsible for aqueous humor (AH) outflow and IOP maintenance, is very sensitive to mechanical forces. However, it is not understood whether Piezo channels, very se...

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Bibliographic Details
Main Authors: Wei Zhu, Fei Hou, Jingwang Fang, Mohammad Reza Bahrani Fard, Yani Liu, Shouyan Ren, Shen Wu, Yunkun Qi, Shangru Sui, A. Thomas Read, Joseph M. Sherwood, Wei Zou, Hongxia Yu, Jingxue Zhang, Darryl R. Overby, Ningli Wang, C. Ross Ethier, KeWei Wang
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221000109