Role of intracellular Ca2+ stores for an impairment of visual processing in a mouse model of Alzheimer's disease

Besides deficits in memory and cognition, impaired visual processing is common for Alzheimer's disease (AD) patients and mouse models of AD but underlying mechanisms still remain unclear. Using in vivo Ca2+ imaging of the mouse primary visual cortex (V1) we tested whether such impairment is cau...

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Bibliographic Details
Main Authors: Nithi Asavapanumas, Bianca Brawek, Peter Martus, Olga Garaschuk
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118303243