Identification of a novel RNA aptamer that selectively targets breast cancer exosomes

Identification of a novel RNA aptamer that selectively targets breast cancer exosomes

Breast cancer is a leading cause of cancer mortality in women. Despite advances in its management, the identification of new options for early-stage diagnosis and therapy of this tumor still represents a crucial challenge. Increasing evidence indicates that extracellular vesicles called exosomes may...

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Bibliographic Details
Main Authors: Carla Lucia Esposito, Cristina Quintavalle, Francesco Ingenito, Deborah Rotoli, Giuseppina Roscigno, Silvia Nuzzo, Renato Thomas, Silvia Catuogno, Vittorio de Franciscis, Gerolama Condorelli
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
aptamers
breast cancer
exosomes
SELEX
early diagnosis
therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121000123

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http://www.sciencedirect.com/science/article/pii/S2162253121000123

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