Genome Editing Tools for Functional Analysis of <i>HNF1A</i> and <i>IL6ST</i> Genes
Genome editing tools, such as TALEN (transcription activator-like effector nuclease) or CRISPR-Cas9 (CRISPR-associated protein-9 nuclease) systems, enable functional studies by targeted gene knockout. They introduce double-stranded breaks (DSBs) into a DNA molecule in a sequence-specific manner, the...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Croatian Chemical Society
2016-06-01
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Series: | Croatica Chemica Acta |
Online Access: | http://hrcak.srce.hr/file/237673 |