Genome Editing Tools for Functional Analysis of <i>HNF1A</i> and <i>IL6ST</i> Genes

Genome editing tools, such as TALEN (transcription activator-like effector nuclease) or CRISPR-Cas9 (CRISPR-associated protein-9 nuclease) systems, enable functional studies by targeted gene knockout. They introduce double-stranded breaks (DSBs) into a DNA molecule in a sequence-specific manner, the...

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Bibliographic Details
Main Authors: Paula Dobrinić, Vanja Tadić, Luka Bočkor, Dora Markulin, Mihaela Tremski, Vlatka Zoldoš, Aleksandar Vojta
Format: Article
Language:English
Published: Croatian Chemical Society 2016-06-01
Series:Croatica Chemica Acta
Online Access:http://hrcak.srce.hr/file/237673