TonEBP Promotes β-Cell Survival under ER Stress by Enhancing Autophagy

TonEBP Promotes β-Cell Survival under ER Stress by Enhancing Autophagy

The endoplasmic reticulum (ER) stress response and autophagy are important cellular responses that determine cell fate and whose dysregulation is implicated in the perturbation of homeostasis and diseases. Tonicity-responsive enhancer-binding protein (TonEBP, also called NFAT5) is a pleiotropic stre...

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Bibliographic Details
Main Authors: Hyun Je Kang, Eun Jin Yoo, Hwan Hee Lee, Seung Min An, Hyun Park, Whaseon Lee-Kwon, Soo Youn Choi, Hyug Moo Kwon
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
NFAT5
autophagy initiation
islet
FIP200
unfolded protein response
UPR
Online Access:https://www.mdpi.com/2073-4409/9/9/1928

Internet

https://www.mdpi.com/2073-4409/9/9/1928

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