Sex-specific effects of serum sulfate level and SLC13A1 nonsense variants on DHEA homeostasis

Sex-specific effects of serum sulfate level and SLC13A1 nonsense variants on DHEA homeostasis

Context: Sulfate is critical in the biotransformation of multiple compounds via sulfation. These compounds include neurotransmitters, proteoglycans, xenobiotics, and hormones such as dehydroepiandrosterone (DHEA). Sulfation reactions are thought to be rate-limited by endogenous sulfate concentration...

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Bibliographic Details
Main Authors: Christina G. Tise, Leslie E. Anforth, Albert E. Zhou, James A. Perry, Patrick F. McArdle, Elizabeth A. Streeten, Alan R. Shuldiner, Laura M. Yerges-Armstrong
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
Serum sulfate
SLC13A1
DHEA
DHEA-S
Sulfation
Online Access:http://www.sciencedirect.com/science/article/pii/S2214426917300010

Internet

http://www.sciencedirect.com/science/article/pii/S2214426917300010

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