Social Stress Increases Vulnerability to High-Fat Diet-Induced Insulin Resistance by Enhancing Neutrophil Elastase Activity in Adipose Tissue

Social Stress Increases Vulnerability to High-Fat Diet-Induced Insulin Resistance by Enhancing Neutrophil Elastase Activity in Adipose Tissue

Social stress (SS) has been linked to the development of cardiovascular disease (CVD), which is closely associated with insulin resistance (IR); however, the causal effect of SS on IR remains unclear. The 8-week-old male C57BL/6 mice were exposed to SS by housing with a larger CD-1 mouse in a shared...

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Bibliographic Details
Main Authors: Shinichiro Motoyama, Hiroyuki Yamada, Keita Yamamoto, Noriyuki Wakana, Kensuke Terada, Masakazu Kikai, Naotoshi Wada, Makoto Saburi, Takeshi Sugimoto, Hiroshi Kubota, Daisuke Miyawaki, Daisuke Kami, Takehiro Ogata, Masakazu Ibi, Chihiro Yabe-Nishimura, Satoaki Matoba
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
social stress
insulin resistance
neutrophil
neutrophil elastase
adipose tissue
heat-shock protein 72
Online Access:https://www.mdpi.com/2073-4409/9/4/996

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https://www.mdpi.com/2073-4409/9/4/996

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