RNA-sequencing analysis of HepG2 cells treated with atorvastatin.

The cholesterol-lowering drug atorvastatin is among the most prescribed drug in the world. Alternative splicing in a number of genes has been reported to be associated with variable statin response. RNA-seq has proven to be a powerful technique for genome-wide splice variant analysis. In the present...

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Bibliographic Details
Main Authors: Camilla Stormo, Marianne K Kringen, Robert Lyle, Ole Kristoffer Olstad, Daniel Sachse, Jens P Berg, Armin P Piehler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4143339?pdf=render