The Actin Cytoskeleton Is Involved in Glial Cell Line-Derived Neurotrophic Factor (GDNF)-Induced Ret Translocation into Lipid Rafts in Dopaminergic Neuronal Cells

The Actin Cytoskeleton Is Involved in Glial Cell Line-Derived Neurotrophic Factor (GDNF)-Induced Ret Translocation into Lipid Rafts in Dopaminergic Neuronal Cells

Glial cell line-derived neurotrophic factor (GDNF), a potential therapeutic factor for Parkinson’s disease (PD), exerts its biological effects through the Ret receptor tyrosine kinase. The redistribution of Ret into lipid rafts substantially influences Ret signaling, but the mechanisms underlying Re...

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Bibliographic Details
Main Authors: Li Li, Haijing Song, Peipei Mu, Ming Xu, Chaoxia Liu, Ying Wang, Yingsong Qin, Shen Sun, Jin Gao, Ting Wang, Dianshuai Gao
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:International Journal of Molecular Sciences
Subjects:
GDNF
Ret
dopaminergic cells
lipid rafts
cytoskeleton
Online Access:https://www.mdpi.com/1422-0067/18/9/1922

Internet

https://www.mdpi.com/1422-0067/18/9/1922

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