Development of Lentiviral Vectors Pseudotyped With Influenza B Hemagglutinins: Application in Vaccine Immunogenicity, mAb Potency, and Sero-Surveillance Studies

Development of Lentiviral Vectors Pseudotyped With Influenza B Hemagglutinins: Application in Vaccine Immunogenicity, mAb Potency, and Sero-Surveillance Studies

Influenza B viruses (IBV) cause respiratory disease epidemics in humans and are therefore components of seasonal influenza vaccines. Serological methods are employed to evaluate vaccine immunogenicity prior to licensure. However, classical methods to assess influenza vaccine immunogenicity such as t...

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Bibliographic Details
Main Authors: Francesca Ferrara, Joanne Marie M. Del Rosario, Kelly A. S. da Costa, Rebecca Kinsley, Simon Scott, Sasan Fereidouni, Craig Thompson, Paul Kellam, Sarah Gilbert, George Carnell, Nigel Temperton
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
influenza B
lentiviral (LV) vector
pseudotype viral particles
pseudotype neutralization
serosurveillance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.661379/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.661379/full

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