p53-Induced Autophagy Regulates Chemotherapy and Radiotherapy Resistance in Multidrug Resistance Cancer Cells
Background Multidrug resistance (MDR), a major problem in oncology therapy, limits the effectiveness of anticancer drugs. Although p53 functions as a tumor suppressor, the associations between p53 status, autophagy, and MDR are complicated and conditional. Method In this report, p53-null human ovar...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2021-10-01
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Series: | Dose-Response |
Online Access: | https://doi.org/10.1177/15593258211048046 |