p53-Induced Autophagy Regulates Chemotherapy and Radiotherapy Resistance in Multidrug Resistance Cancer Cells

Background Multidrug resistance (MDR), a major problem in oncology therapy, limits the effectiveness of anticancer drugs. Although p53 functions as a tumor suppressor, the associations between p53 status, autophagy, and MDR are complicated and conditional. Method  In this report, p53-null human ovar...

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Bibliographic Details
Main Authors: Shumei Ma, Dejuan Kong, Xinxin Fu, Lin Liu, Yi Liu, Chang Xue, Zhujun Tian, Lan Li, Xiaodong Liu
Format: Article
Language:English
Published: SAGE Publishing 2021-10-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/15593258211048046