Phase transitions in the multi-cellular regulatory behavior of pancreatic islet excitability.

The pancreatic islets of Langerhans are multicellular micro-organs integral to maintaining glucose homeostasis through secretion of the hormone insulin. β-cells within the islet exist as a highly coupled electrical network which coordinates electrical activity and insulin release at high glucose, bu...

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Bibliographic Details
Main Authors: Thomas H Hraha, Matthew J Westacott, Marina Pozzoli, Aleena M Notary, P Mason McClatchey, Richard K P Benninger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25188228/pdf/?tool=EBI