TGF-β/Smad signaling pathway as a candidate for EMAST phenotype in colorectal cancer patients

TGF-β/Smad signaling pathway as a candidate for EMAST phenotype in colorectal cancer patients

Objective: Elevated microsatellite alteration at selected tetranucleotide repeats (EMAST) is a prognostic biomarker in colorectal cancer (CRC). EMAST phenotype appears to be linked to deficiency in DNA mismatch repair (MMR) proteins including MSH3. The TGF-β signaling pathway has a pivotal role in t...

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Bibliographic Details
Main Authors: A. Torshizi Esfahani, S. Seyedna, E. Nazemalhosseini Mojarad, A. Majd, H. Asadzadeh Aghdaei
Format: Article
Language:English
Published: Verduci Editore 2020-01-01
Series:World Cancer Research Journal
Subjects:
microsatellite instability
elevated microsatellite alteration at selected tetranucleotide repeats (emast)
canonical tgf-ß signaling pathway
colorectal neoplasms
Online Access:https://www.wcrj.net/wp-content/uploads/sites/5/2020/01/e1470-TGF-bSmad-signaling-pathway-as-a-candidate-for-EMAST-phenotype-in-colorectal-cancer-patients-1.pdf

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https://www.wcrj.net/wp-content/uploads/sites/5/2020/01/e1470-TGF-bSmad-signaling-pathway-as-a-candidate-for-EMAST-phenotype-in-colorectal-cancer-patients-1.pdf

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