Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone

Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone

The mechanisms by which aging induces muscle impairment are not well understood yet. We studied the impact of aging on Ca2+ homeostasis in the slow-twitch soleus and the fast-twitch extensor digitorum longus (EDL) muscles of aged rats by using the fura-2 fluorescent probe. In both muscles aging incr...

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Bibliographic Details
Main Authors: Bodvael Fraysse, Jean-François Desaphy, Jean-François Rolland, Sabata Pierno, Antonella Liantonio, Viviana Giannuzzi, Claudia Camerino, M. Paola Didonna, Daniela Cocchi, Annamaria De Luca, Diana Conte Camerino
Format: Article
Language:English
Published: Elsevier 2006-02-01
Series:Neurobiology of Disease
Subjects:
Aging
Skeletal muscle
Resting calcium concentration
Fura-2
Growth hormone
Sarcolemmal permeability to calcium
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105002159

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http://www.sciencedirect.com/science/article/pii/S0969996105002159

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