Structural insights into the RNA methyltransferase domain of METTL16
Abstract N 6-methyladenosine (m6A) is an abundant modification in messenger RNA and noncoding RNAs that affects RNA metabolism. Methyltransferase-like protein 16 (METTL16) is a recently confirmed m6A RNA methyltransferase that methylates U6 spliceosomal RNA and interacts with the 3′-terminal RNA tri...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2018-03-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-018-23608-8 |