Small interfering RNA targeting m2 gene induces effective and long term inhibition of influenza A virus replication.

RNA interference (RNAi) provides a powerful new means to inhibit viral infection specifically. However, the selection of siRNA-resistant viruses is a major concern in the use of RNAi as antiviral therapeutics. In this study, we conducted a lentiviral vector with a H1-short hairpin RNA (shRNA) expres...

Full description

Bibliographic Details
Main Authors: Hong-Yan Sui, Guang-Yu Zhao, Jian-Dong Huang, Dong-Yan Jin, Kwok-Yung Yuen, Bo-Jian Zheng
Format: Article
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access: