Single nucleotide polymorphisms at the microRNA-binding site of KIAA0423 are associated with colorectal cancer

MicroRNAs (miRNAs) binding to the 3′-untranslated regions (3′UTRs) of messenger RNAs to mediate translation and thereby regulate cell differentiation, apoptosis and tumorigenesis. Single nucleotide polymorphisms (SNPs) in the 3′UTRs of genes would alter the binding affinity between targeted genes an...

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Bibliographic Details
Main Authors: Yue Zhao, Huichai Yang, Xiaoxu Luo, Cuiju Wang, Ruixing Zhang, Zhanjun Guo
Format: Article
Language:English
Published: Taylor & Francis Group 2016-11-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
CRC
Online Access:http://dx.doi.org/10.1080/13102818.2016.1212672