Use of Radical Oxygen Species Scavenger Nitrones to Treat Oxidative Stress-Mediated Hearing Loss: State of the Art and Challenges

Use of Radical Oxygen Species Scavenger Nitrones to Treat Oxidative Stress-Mediated Hearing Loss: State of the Art and Challenges

Nitrones are potent antioxidant molecules able to reduce oxidative stress by trapping reactive oxygen and nitrogen species. The antioxidant potential of nitrones has been extensively tested in multiple models of human diseases. Sensorineural hearing loss has a heterogeneous etiology, genetic alterat...

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Bibliographic Details
Main Authors: Isabel Varela-Nieto, Silvia Murillo-Cuesta, Lourdes Rodríguez-de la Rosa, María Jesús Oset-Gasque, José Marco-Contelles
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
antioxidants
free radicals
sensorineural hearing loss
N-acetyl-L-cysteine
NXY-059
4-OHPBN
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.711269/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.711269/full

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