Protracted Administration of L-Asparaginase in Maintenance Phase Is the Risk Factor for Hyperglycemia in Older Patients with Pediatric Acute Lymphoblastic Leukemia.

Protracted Administration of L-Asparaginase in Maintenance Phase Is the Risk Factor for Hyperglycemia in Older Patients with Pediatric Acute Lymphoblastic Leukemia.

Although L-asparaginase related hyperglycemia is well known adverse event, it is not studied whether the profile of this adverse event is affected by intensification of L-asparaginase administration. Here, we analyzed the profile of L-asparaginase related hyperglycemia in a 1,176 patients with pedia...

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Main Authors: Hideki Yoshida, Toshihiko Imamura, Akiko M Saito, Yoshihiro Takahashi, So-ichi Suenobu, Daiichiro Hasegawa, Takao Deguchi, Yoshiko Hashii, Hirohide Kawasaki, Mikiya Endo, Hiroki Hori, Nobuhiro Suzuki, Yoshiyuki Kosaka, Koji Kato, Keiko Yumura-Yagi, Junichi Hara, Megumi Oda, Atsushi Sato, Keizo Horibe, Japan Association of Childhood Leukemia Study
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4552641?pdf=render

Internet

http://europepmc.org/articles/PMC4552641?pdf=render

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