Molecular Docking Studies of Marine Diterpenes as Inhibitors of Wild-Type and Mutants HIV-1 Reverse Transcriptase

Molecular Docking Studies of Marine Diterpenes as Inhibitors of Wild-Type and Mutants HIV-1 Reverse Transcriptase

AIDS is a pandemic responsible for more than 35 million deaths. The emergence of resistant mutations due to drug use is the biggest cause of treatment failure. Marine organisms are sources of different molecules, some of which offer promising HIV-1 reverse transcriptase (RT) inhibitory activity, suc...

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Bibliographic Details
Main Authors: Alessandra M. T. de Souza, Monique A. de Brito, Lucio M. Cabral, Magaly G. Albuquerque, Juliana F. R. Mello, Carlos R. Rodrigues, Helena C. Castro, Valéria L. Teixeira, Leonardo A. Miceli
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Marine Drugs
Subjects:
HIV-1
mutants
molecular docking
brown algae diterpenes
antiviral
reverse transcriptase
Online Access:http://www.mdpi.com/1660-3397/11/11/4127

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http://www.mdpi.com/1660-3397/11/11/4127

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